中国学者近期发表的论文
1.	Synthesis and Anti-HCV Activities of 4'-Fluoro-2'-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4'-Fluoro-2'- C-methyluridine 5'-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection. Author: Wang G1, Dyatkina N1, Prhavc M1, Williams C1, Serebryany V1, Hu Y2, Huang Y2, Wan J2, Wu X2, Deval J1, Fung A1, Jin Z1, Tan H1, Shaw K1, Kang H1, Zhang Q1, Tam Y1, Stoycheva A1, Jekle A1, Smith DB1, Beigelman L1. Journal: J Med Chem. 2019 May 9;62(9):4555-4570. doi: 10.1021/acs.jmedchem.9b00143. Epub 2019 Apr 19.    PubMed      DOI
2.	Rational Design of Short Peptide Variants by Using Kunitzin-RE, an Amphibian-Derived Bioactivity Peptide, for Acquired Potent Broad-Spectrum Antimicrobial and Improved Therapeutic Potential of Commensalism Coinfection of Pathogens. Author: Yang Z1, He S1, Wang J1, Yang Y1, Zhang L1, Li Y2, Shan A1. Journal: J Med Chem. 2019 May 9;62(9):4586-4605. doi: 10.1021/acs.jmedchem.9b00149. Epub 2019 Apr 19.    PubMed      DOI
3.	Targeting the Thioredoxin System as a Strategy for Cancer Therapy. Author: Bian M1, Fan R1, Zhao S1,2, Liu W1,3. Journal: J Med Chem. 2019 Apr 16. doi: 10.1021/acs.jmedchem.8b01595. [Epub ahead of print]    PubMed      DOI
4.	Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. Author: Qin M1, Cao Q1, Zheng S1, Tian Y1, Zhang H2, Xie J2, Xie H3, Liu Y1, Zhao Y1, Gong P1. Journal: J Med Chem. 2019 May 9;62(9):4703-4715. doi: 10.1021/acs.jmedchem.9b00312. Epub 2019 Apr 19.    PubMed      DOI
5.	Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. Author: Zhang Y1,2,3, Wu X1,2,3, Xue X1,4, Li C1, Wang J5, Wang R1, Zhang C1,6, Wang C1,2,3, Shi Y1,2,3, Zou L1,2,3, Li Q1,2,3, Huang Z, Hao X7, Loomes K8, Wu D9, Chen HW, Xu J9, Xu Y1,3. Journal: J Med Chem. 2019 May 9;62(9):4716-4730. doi: 10.1021/acs.jmedchem.9b00327. Epub 2019 Apr 22.    PubMed      DOI
6.	Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid Differentiation Protein 2/Toll-like Receptor 4 Antagonists for Treatment of Acute Lung Injury. Author: Liu Z1, Chen L2, Yu P1,3, Zhang Y1, Fang B1, Wu C1, Luo W1, Chen X1, Li C1, Liang G1,2. Journal: J Med Chem. 2019 Apr 29. doi: 10.1021/acs.jmedchem.9b00316. [Epub ahead of print]    PubMed      DOI
7.	Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. Author: Huang L1, Li H1, Li L2, Niu L1, Seupel R3,4, Wu C1, Cheng W1, Chen C1, Ding B1, Brennan PE3,4, Yang S1. Journal: J Med Chem. 2019 May 9;62(9):4526-4542. doi: 10.1021/acs.jmedchem.9b00096. Epub 2019 Apr 30.    PubMed      DOI
8.	Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. Author: Crespo RA1, Dang Q2, Zhou NE1, Guthrie LM3, Snavely TC1, Dong W1, Loesch KA1, Suzuki T4, You L4, Wang W4, O'Malley T5, Parish T5, Olsen DB2, Sacchettini JC1. Journal: J Med Chem. 2019 May 9;62(9):4483-4499. doi: 10.1021/acs.jmedchem.9b00020. Epub 2019 Apr 19.    PubMed      DOI
9.	Fuplatin: An Efficient and Low-Toxic Dual-Prodrug. Author: Zhang R1, Song XQ1, Liu RP1, Ma ZY1, Xu JY1. Journal: J Med Chem. 2019 May 9;62(9):4543-4554. doi: 10.1021/acs.jmedchem.9b00128. Epub 2019 Apr 30.    PubMed      DOI
10.	Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. Author: Wang Z1, Jiang X1, Zhang X1,2, Tian G3, Yang R3, Wu J3, Zou X3, Liu Z4, Yang X4, Wu C4, Shi J4, Li J1, Suo J1, Wang Y1, Zhang R1, Xu Z1, Gong X1,5, He Y1, Zhu W1,2, Aisa HA5, Jiang H1,2, Xu Y1,2, Shen J1,2. Journal: J Med Chem. 2019 May 23;62(10):4979-4990. doi: 10.1021/acs.jmedchem.9b00123. Epub 2019 May 8.    PubMed      DOI

同类著名期刊名称 h-index CiteScore EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 135 8.30 Marine Drugs 84 5.10 CURRENT TOPICS IN MEDICINAL CHEMISTRY 104 6.60 MINI-REVIEWS IN MEDICINAL CHEMISTRY 79 3.40 Medicinal Chemistry 39 3.20 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 133 5.10 NATURAL PRODUCT RESEARCH 42 3.30 MEDICINAL CHEMISTRY RESEARCH 38 3.20 Records of Natural Products 24 2.30 Letters in Drug Design & Discovery 28 1.80

中科院JCR同大类学科的热搜期刊 浏览次数 MEDICINE 301009 CANCER RESEARCH 166233 Molecular Medicine Reports 165047 International Journal of Nanomedicine 164759 CANCER LETTERS 159837 JOURNAL OF ETHNOPHARMACOLOGY 142065 BIOMEDICINE & PHARMACOTHERAPY 141153 Theranostics 136281 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 136236 International Journal of Environmental Research and Public Health 133900